Tissue engineering of genetically competent corneal/conjunctival cells for subsequent grafting in human medicine

Dept 58 - International Relations Department
Dept 58 - International Relations Department

Published

Updated 23-12-2014
  • region changed

Project
RegionNational coverage
Title of the ProgrammeCzech-Norwegian Research Programme
Title of the ProjectTissue engineering of genetically competent corneal/conjunctival cells for subsequent grafting in human medicine
Number of the Project7F14156
Project Promoter

Charles University in Prague

www.cuni.cz

Name of Norwegian Partner(s)

Oslo University Hospital, NILU – Norwegian Institute of Air Reserarch

Name of Local Partner(s)

University Hospital Kralovske Vinohrady

Objective of the Project

The overall objective of this proposal is to help to alleviate the dual problem facing transplantation medicine, of shortage of donor tissues, and the relatively short storage time. We will develop novel, improved protocols for preparation of corneal (endothelial and epithelial) and conjunctival (epithelial and goblet) cells for potential grafting in human medicine. Throughout, we will monitor the viability of cells and tissues using established tests for DNA integrity and DNA repair capability. Vitrification will be introduced as a potential method for indefinite storage of cells/tissue for grafting.

Approved grant

872 491 EUR

Project DurationStart date: 7th August 2014, End date: 30th April 2017